Case Reports

Case Studies of Atypical RLS

Turrini, A., Raggi, A., Calandra-Buonaura, G., Martinelli, P., Ferri, R., & Provini, F. (2018). Not only limbs in atypical restless legs syndrome. Sleep Medicine Reviews, 38: 50-55. doi: 10.1016/j.smrv.2017.03.007

Restless Abdomen

Wang, X.-X., Xiao-Ying, Z., Dong, J.-W., Ondo, W. G., & Wu, Y.-C. (2020) Restless abdomen: A spectrum or a phenotype variant of restless legs syndrome? BMC Neurology, 20, 298-305. doi: 10.1186/s12883-020-01875-1

Prakash, S. & Prakash, A. (2021) Dopa responsive irritable bowel syndrome: restless bowel syndrome or a gastrointestinal variant of restless legs syndrome? BMJ Case Reports, 14. doi: 10.1136/bc-2020-240686

Perez-Diaz, H., Iranzo, A., Rye, D. B., & Santamaria, J. (2011). Restless abdomen: A phenotypic variant of restless legs syndrome. Neurology, 77: 1283-1286. doi: 10.1212/WNL.0b013e318230207a

Suzuki, M., Yamada, K., Kanamori, T., Konno, C., Konno, M., Takahashi, S., Aramaki, O., Takayama, T., & Uchiyama, M. (2013). Abdominal paresthesia resembling restless legs syndrome successfully treated with iron supplement therapy: A case report. Journal of the Neurological Sciences, 336: 291-292. doi: 10.1016/j.jns.2013.10.042

Sun, Z., Tan, Y., Li, Z., Yang, L., Sun, X., Du, Y., & Chen, Y. (2022). Teaching Video NeuroImage: Restless Abdomen. Neurology, 98: 858-859. doi: 10.1212/WNL.0000000000200595

Restless Upper Limbs

Gupta, R., Lahan, V., & Goel, D. (2013). Restlessness in right upper limb as sole presentation of restless legs syndrome. Journal of Neurosciences in Rural Practice, 4(1), 78-80. doi: 10.4103/0976-3124.105625

Restless Chest

Ishizuka, K. & Ohira, Y. (2022). Restless chest syndrome: A rare variant of restless legs syndrome. European Journal of Case Reports in Internal Medicine. doi: 10.12890/2022_003398

Restless Genitalia

Sforza, E., Hupin, D., & Roche, F. (2017). Restless genital syndrome: Differential diagnosis and treatment with pramipexole. Journal of Clinical Sleep Medicine, 13(9): 1109-1110. doi: 10.5664/jcsm.6736

RLS and Nicotine Use

Oksenberg, A. (2010). Alleviation of severe restless legs syndrome (RLS) symptoms by cigarette smoking. Journal of Clinical Sleep Medicine, 6(5): 489-490. doi: 

Lahan, V., Ahmad, S., & Gupta, R. (2012). RLS relieved by tobacco chewing: Paradoxical role of nicotine. Neurological Science, 33: 1209-1210. doi: 10.1007/s10072-011-0882-z 

RLS Co-Occurring with Other Diagnoses

Winkelman, J. W., Grant, N. R., Molay, F., Stephen, C. D., Sadjadi, R., & Eichler, F. S. (2022). Restless legs syndrome in X-linked adrenoleukodystrophy. Sleep Medicine, 91, 31-34. doi: 10.1016/j.sleep.2022.02.008

Ulfberg, J., Sielaff, B., & Grote, L. (2019). A case of severe delayed sleep-wake phase disorder and simultaneous restless legs syndrome. Sleep and Vigilance. doi: 10.1007/s41782-019-00071-7

Case Reports of Sex Differences in RLS

Manconi, M., Ulfberg, J., Berger, K., Ghorayeb, I., Wesstrom, J., Fulda, S., Allen, R. P., & Pollmacher, T. (2011). When gender matters: Restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group. Sleep Medicine Reviews, 8(6), 1-11. doi: 10.1016/j.smrv.2011.08.006